Detalhes essenciais
Quantidade (peças):25
MOQ:1
Tempo de entrega:ready cargo
Envio:快递, 空运, 陆运, 海运
número da especificação:616204-22-9
Introdução do Produto
Acetyl Hexapeptide-8, with the CAS number 616204 - 22 - 9, is a popular ingredient in high - end cosmetics, commonly known as Argireline1.
Product Introduction
Acetyl Hexapeptide-8 is a peptide composed of six amino acids, with the chemical formula C₃₄H₆₀N₁₄O₁₂S and a molecular weight of approximately 888.991. It is a white crystalline powder, soluble in water and glycerol, and is most stable at pH 5 - 76.
Its main function is anti - wrinkle. It works by competing with SNAP - 25 for binding sites, interfering with the formation of the SNARE complex, thus blocking the release of acetylcholine, weakening muscle contraction, and reducing the appearance of dynamic and expression lines. In addition, it can stimulate the skin's own collagen production, increase skin thickness and elasticity, and has antioxidant properties, which can scavenge free radicals. It also helps to enhance the skin's moisture - retaining ability, making the skin smoother, more delicate and shiny.
Acetyl Hexapeptide-8 is widely used in anti - wrinkle and firming skin care products, such as serums, creams, and eye creams. It is often used in combination with other anti - aging ingredients, such as sodium hyaluronate, niacinamide, etc., to achieve better anti - aging effects. According to relevant regulations, the safe use concentration of Acetyl Hexapeptide-8 in leave - on cosmetics is no higher than 0.005%, and in rinse - off cosmetics is no higher than 0.000005%6.
Technical Data Table
Property | Details |
---|---|
CAS Number | 616204 - 22 - 9 |
Chemical Formula | C₃₄H₆₀N₁₄O₁₂S |
Molecular Weight | About 888.99 |
Amino Acid Sequence | Ac - Glu - Glu - Met - Gln - Arg - Arg - NH2 |
Appearance | White to off - white powder |
Solubility | Soluble in water, glycerol |
Optimal pH | 5 - 7 |
Recommended Addition Amount | 50 - 500ppm6 |
Application Picture

Acetyl Hexapeptide-8 (CAS 616204 - 22 - 9) Product FAQs
What is Acetyl Hexapeptide-8?
Acetyl Hexapeptide-8 is a synthetic peptide compound made up of six amino acids. It's also known as Argireline. With the chemical formula C34H60N14O12S, it appears as a white powder.
How does it work in skincare?
It inhibits nerve - to - muscle communication, locally blocking nerve transmission signals of muscle contraction. This relaxes facial muscles, reducing dynamic, static, and fine lines. It also reorganizes collagen elasticity, increases elastin activity, and helps smooth wrinkles.
What are its main skincare benefits?
Anti - wrinkle: Effective in reducing fine lines and wrinkles, especially those caused by facial expressions like crow's feet and forehead lines.
Firming and Lifting: Improves skin firmness and elasticity, giving a more lifted and youthful look.
Moisturizing: Some products with it provide hydration along with anti - aging benefits.
In which cosmetic products is it used?
It's commonly found in anti - wrinkle creams, firming and lifting products, eye care products (such as eye creams and gels), moisturizers, and even some makeup products like foundations and primers.
Is it safe to use?
Generally, it is considered safe. It has a relatively low side - effect profile. However, as with any ingredient, some individuals may be sensitive to it. It's always advisable to do a patch test before using a new product containing it. The Cosmetic Ingredient Review (CIR) has evaluated its safety for use in cosmetics at certain concentrations.
How should it be stored?
It's recommended to store it in a cool, dry, and well - ventilated place. Usually, a storage temperature of 2 - 8 °C is suitable for short - term storage, and for long - term storage, - 20 °C is better.
What is its solubility?
Acetyl Hexapeptide-8 is soluble in water and acetic acid, which makes it suitable for incorporation into various aqueous - based cosmetic formulations.